8/6/09

Broccoli and tomatoes enriched with bioactive chemicals

A line of work that I fully agree with.

Feeding Tomato and Broccoli Powders Enriched with Bioactives Improves Bioactivity Markers in Rats

Ann G. Liu, Sonja E. Volker, Elizabeth H. Jeffery and John W. Erdman, Jr.

Division of Nutritional Sciences and Department of Food Science and Human Nutrition, 905 South Goodwin Avenue, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801

J. Agric. Food Chem., Article ASAP Publication Date (Web): August 3, 2009

Abstract

Many studies have evaluated the cancer -preventive potential of individual bioactives from tomatoes and broccoli, but few have examined them within the context of a whole food.

Male Copenhagen rats were fed diets containing 10% standard tomato powder, tomato enriched with lycopene or total carotenoids, standard broccoli floret, broccoli sprouts, or broccoli enriched with indole glucosinolates or selenium for 7 days. All broccoli diets increased the activity of colon quinone reductase (NQO1). Indole glucosinolate-enriched broccoli and selenium-enriched broccoli increased hepatic NQO1 and cytochrome P450 1A activity.

These results demonstrate that the bioactive content of vegetables affects both tissue content of bioactives and activity of detoxification enzymes. Enhancing bioactive content of tomatoes and broccoli may enhance efficacy in the prevention of prostate cancer.

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